Can there ever be a meaningful distinction in science between the "unknown" and

Can there ever be a meaningful distinction in science between the "unknown" and

Can there ever be a meaningful distinction in science between the "unknown" and the "unknowable"? I see no reason why science should not,in 100,000 years or so, unlock what now seem to be unknowable questions like the nature of a Prime Mover, if he exists, simply by accruing more and more knowledge of the universe. We know pretty much what happened a trillionth of a second after the Big Bang and we acquired this knowledge in about 100 years so why assume everything before that is unknowable? Surely the scientific method would insist that this is "presently unknown". Is it that metaphysics and the persistence of religious belief color our approach? Is "unknowable" even a valid term in philosophy, and, if so, what definitive, unassailable examples are there of it (which would also apply, say, 100,000 years from now)? Thanks in advance.

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