Suppose that you believe in determinism, how could you live with that? Sometimes

Suppose that you believe in determinism, how could you live with that? Sometimes

Suppose that you believe in determinism, how could you live with that? Sometimes everything seems clearly determined by circumstances (science...), but it's hard to believe that someone who has murdered someone is not really guilty - 'it's the just the circumstances that influenced him to do such an act'. Or is there some kind of determinism where it is possible to be guilty? I hope you can help me out here.

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